Unit Overview

Students investigate reproduction at genetic levels discovering asexual versus sexual reproduction differences. Through solving sibling appearance mysteries examining chromosomes or comparing algae and frog reproduction types, conducting inheritance pattern investigations using Punnett squares predicting offspring traits, and engineering genetic diversity projects, students learn how sexual reproduction creates variation while asexual reproduction produces genetically identical offspring.

Lesson Overview

Solve: Celebrity Family Traits + DNA Mystery

Algae accuse frogs Paulie and Nicole of lying about being siblings—they look so different! Students follow Mosa investigating at the genetic level, discovering crucial reproduction differences. Algae reproduce asexually, simply replicating with all mother's genes passing unchanged, creating identical offspring. Frogs reproduce sexually—sperm fertilizes egg, mixing genes from both parents. This creates genetic variation explaining why Paulie and Nicole look different despite being siblings. Students must identify which potential father frog is theirs by matching inherited traits.

Make: Compare Asexual & Sexual Reproduction

Your students design two alien families from scratch—one that reproduces sexually, one asexually—and discover how genetic variation (or the lack of it) shapes each generation. It's hands-on genetics with a creative twist, turning abstract inheritance patterns into something they can build, compare, and argue about.

Engineer: Genetically Engineer a Solution to an Alien Problem

Here's the challenge: start with a desired trait in an offspring and work backward. What parent combination would you need? Students use reverse engineering to think like geneticists, designing ideal parent pairings to produce specific outcomes. You pose the problem; they wrestle with the genetics—and discover that inheritance isn't always as predictable as it seems.

Next Generations Science Standards

MS-LS3-2
Develop and use a model to describe why asexual reproduction results in offspring with identical genetic information and sexual reproduction results in offspring with genetic variation.
MS-LS4-5
Gather and synthesize information about the technologies that have changed the way humans influence the inheritance of desired traits in organisms.

Science & Engineering Practices

  • Developing and Using Models
  • Obtaining, Evaluating, and Communicating Information (Oral Presentation)

Disciplinary Core Ideas

  • Inheritance of Traits
  • Natural Selection
  • Variation of Traits

Cross Cutting Concepts

  • Cause and Effect
  • Connections to Engineering, Technology, and Applications of Science
  • Connections to Nature of Science
  • Interdependence of Science, Engineering, and Technology
  • Science Addresses Questions About the Natural and Material World

Inquiry Scale

  • Each lesson in the unit has an Inquiry Scale that provides directions on how to implement the lesson at the level that works best for you and your students.
  • “Level 1” is the most teacher-driven, and recommended for students in 4th-5th grades. “Level 4” is the most student-driven, and recommended for students in 7th-8th grades.
  • For differentiation within the same grade or class, use different inquiry levels for different groups of students who may require additional support or an extra challenge.

Common Misconceptions

  • Learners can be confused by the idea of genes coding for proteins which determine traits because they have only heard the word protein in the context of food. Highlight that the protein in the food we eat is broken down into smaller parts called amino acids. Those amino acids are then used as building blocks for this process.
  • Learners are initially uncertain about the difference between a gene and a trait, so take time to highlight this both in the episode and the vocabulary mind map before moving on to the “Make.”
  • Learners at first believe that if the offspring have a physical trait in common with one parent, that trait comes wholly from one parent. Emphasize that offspring get half their DNA from mom and half from dad, and this applies to every trait. It is helpful to scaffold this during the “Make” by showing one allele coming from mom and one from dad to create the trait in the offspring.

Vocabulary

    • Gene
    • Chromosome
    • Trait
    • Mutation
    • Asexual Reproduction
    • Sexual Reproduction

Content Expert

  • Bruce Grant, Ph.D
    Professor of Biology Emeritus; College of William & Mary

Resources

  • Powerpoints for Make and Design
  • Vocabulary Cards
  • Vocabulary Mind Map
  • Solve Student Handout
  • Make Student Handout
  • Design Student Handout